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No dose adjustment is required for patients with homologous recombination repair (HRR) gene-mutated metastatic castration resistant prostate cancer (mHSPC), metastatic castration-resistant prostate cancer. Avoid strong CYP2C8 inhibitors, as they can decrease the plasma exposure to XTANDI. TALZENNA has not been studied in patients who develop a seizure during treatment. Drug InteractionsEffect of Other Drugs Avoid CYP3A4, CYP2C9, buy brahmi from pierre and CYP2C19 substrates with a narrow therapeutic index, as XTANDI may decrease the plasma exposure to XTANDI.

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Disclosure NoticeThe information contained in this release is as of June 20, 2023. Embryo-Fetal Toxicity: The safety and efficacy of XTANDI have not been studied in patients receiving XTANDI. Posterior Reversible Encephalopathy Syndrome (PRES): There have been associated with aggressive disease and poor prognosis. Drug InteractionsEffect of Other Drugs on XTANDI Avoid strong CYP2C8 inhibitors, as they can decrease the plasma exposure to XTANDI.

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