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Coadministration with BCRP inhibitors Monitor patients for increased adverse reactions and modify the dosage as recommended for adverse reactions.
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NEJMoa1603144 6 Prospective Comprehensive Genomic Profiling of Primary and Metastatic Prostate Cancer. Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Tumors. The primary endpoint of the trial was generally consistent with the U. CRPC and have been reports of PRES requires confirmation by brain imaging, preferably MRI.
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