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Stop taking Kaletra and call your doctor at once if you have:

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  • itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

  • high blood sugar (increased thirst, increased urination);

  • penis erection that is painful or lasts 4 hours or longer (if you take Kaletra with erectile dysfunction medication);

  • muscle weakness, tired feeling, joint or muscle pain, feeling short of breath; or

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Kaletra may increase your risk of certain infections or autoimmune disorders by changing the way your immune system works. Symptoms may occur weeks or months after you start treatment with Kaletra. Tell your doctor if you have:

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